Serological tests: The virus neutralisation test and various enzyme-linked immunosorbent assays
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چکیده
The disease is characterised by clinical signs of the upper respiratory tract, such as a (muco)purulent nasal discharge, hyperaemia of the muzzle (red nose disease) and by conjunctivitis. Signs of general illness are fever, depression, inappetence, abortions and reduced milk yield. The virus can also infect the genital tract and cause pustular vulvovaginitis and balanoposthitis. Postmortem examinations reveal rhinitis, laryngitis and tracheitis. Mortality is low, and most infections run a subclinical course. Secondary bacterial infections can lead to more severe respiratory disease, and BoHV-1 could play a role in multifactor diseases such as ‘shipping fever’.
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